Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562918 | 0.85 | CA12 (0.42) | L3MBTL1NSD2GAAPLCG1DNMT1 | |
| SCHEMBL8564866 | 0.76 | EGFR (0.41) | L3MBTL1EGFRALDH1A1TDP1HPGD | |
| SCHEMBL8596876 | 0.76 | ALDH1A1 (0.39) | L3MBTL1NSD2GAAPLCG1DNMT1 | |
| SCHEMBL8598258 | 0.76 | L3MBTL1 (0.47) | L3MBTL1KDM4ECA9CA12ALDH1A1 | |
| SCHEMBL8564092 | 0.75 | MAPK1 (0.47) | L3MBTL1NSD2GAAPLCG1DNMT1 | |
| SCHEMBL5252473 | 0.74 | TDP1 (0.48) | L3MBTL1GPR35EGFRALDH1A1TDP1 | |
| SCHEMBL8924026 | 0.74 | TSHR (0.38) | L3MBTL1KDM4ECA9CA12CA1 | |
| SCHEMBL8568601 | 0.74 | ALDH1A1 (0.56) | EGFRALDH1A1HPGDLMNAMAPT | |
| SCHEMBL8598914 | 0.74 | TXNRD1 (0.46) | L3MBTL1EGFRALDH1A1TDP1LMNA | |
| SCHEMBL8633335 | 0.74 | CA12 (0.33) | CA9CA12CA1CA2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |