Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596876 | 0.81 | ALDH1A1 (0.39) | CA12CA1CA2CA9EGFR | |
| SCHEMBL8924026 | 0.79 | TSHR (0.38) | CA12CA1CA2CA9EGFR | |
| SCHEMBL8602043 | 0.78 | KDM4E (0.38) | EGFRMAPTALDH1A1LMNAHTT | |
| SCHEMBL8624452 | 0.77 | L3MBTL1 (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8562212 | 0.77 | PIN1 (0.46) | CA1CA2CA9EGFRALDH1A1 | |
| SCHEMBL8626672 | 0.76 | CA12 (0.33) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8562918 | 0.75 | CA12 (0.42) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8563003 | 0.74 | L3MBTL1 (0.45) | CA12CA1CA2CA9EGFR | |
| SCHEMBL8628904 | 0.73 | CA12 (0.38) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8630572 | 0.72 | CA12 (0.31) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |