Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563279 | 0.90 | AVPR2 (0.48) | MEN1KMT2AALDH1A1AVPR2AVPR1A | |
| SCHEMBL8557610 | 0.90 | MAPT (0.52) | NPC1RAB9AKMT2AALDH1A1TP53 | |
| SCHEMBL8563047 | 0.84 | AVPR1A (0.51) | RAB9AKMT2ANAMPTMAPTKDM4E | |
| SCHEMBL8559901 | 0.81 | AVPR2 (0.63) | AVPR2AVPR1A | |
| SCHEMBL8557927 | 0.81 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL8561948 | 0.81 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL8556562 | 0.80 | KCNK3 (0.44) | NAMPTAVPR2AVPR1A | |
| SCHEMBL8563496 | 0.80 | AVPR2 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8557883 | 0.79 | MEN1 (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8560617 | 0.79 | AVPR1A (0.49) | RAB9AMAPTLMNASMN1; SMN2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |