Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560873 | 0.80 | ACHE (0.60) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8556372 | 0.80 | KCNJ5 (0.51) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8560800 | 0.78 | AVPR2 (0.79) | AVPR1AAVPR2 | |
| SCHEMBL8557068 | 0.77 | AVPR2 (0.57) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8564119 | 0.77 | AVPR2 (0.68) | AVPR1AAVPR2 | |
| SCHEMBL8560660 | 0.76 | NPC1 (0.54) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8555952 | 0.76 | NAMPT (0.51) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8559349 | 0.76 | AVPR2 (0.60) | AVPR1AAVPR2 | |
| SCHEMBL8558993 | 0.76 | AVPR2 (0.65) | AVPR1AAVPR2 | |
| SCHEMBL8556851 | 0.76 | AVPR2 (0.58) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |