Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242706 | 0.89 | TNKS2 (0.35) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL11098325 | 0.87 | LMNA (0.40) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL8563125 | 0.86 | IMPDH2 (0.49) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL24784363 | 0.85 | LMNA (0.42) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL24783641 | 0.85 | LMNA (0.42) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL7971157 | 0.81 | CA2 (0.46) | IMPDH2IMPDH1CA2CA4 | |
| SCHEMBL14896505 | 0.81 | TSHR (0.41) | IMPDH2IMPDH1 | |
| SCHEMBL14894561 | 0.79 | ALOX5 (0.33) | — | |
| SCHEMBL11173917 | 0.78 | LMNA (0.34) | IMPDH1 | |
| SCHEMBL14894616 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549366-B1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5338855-A | Treating diabetes or hyperlipemia | SANKYO COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0549366-A1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |