Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 13/20 | 0.34 |
| ▸ | EDNRA | P25101 | 13/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787397 | 0.80 | SLC1A3 (0.40) | KMT2ACYP2C19 | |
| SCHEMBL9187436 | 0.80 | EDNRB (0.32) | EDNRBEDNRAKMT2AMAPTKIF11 | |
| SCHEMBL8085861 | 0.77 | KCNN4 (0.36) | KMT2AMAPTKIF11KCNN4CYP2C19 | |
| SCHEMBL7624597 | 0.68 | KIF11 (0.32) | KIF11 | |
| SCHEMBL9261168 | 0.68 | MAPT (0.34) | EDNRBEDNRAKMT2AMAPTKIF11 | |
| SCHEMBL8571936 | 0.67 | MEN1 (0.35) | EDNRBEDNRAKMT2AMAPTKIF11 | |
| SCHEMBL8784381 | 0.66 | KCNN4 (0.40) | KMT2AMAPTKCNN4CYP2C19HIF1A | |
| SCHEMBL3786557 | 0.65 | CYP2C19 (0.47) | KMT2APOLBMAPTKCNN4CYP2C19 | |
| SCHEMBL7706278 | 0.65 | SMN1; SMN2 (0.36) | EDNRBEDNRAKMT2APOLBKIF11 | |
| SCHEMBL8567588 | 0.65 | ALDH1A1 (0.38) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728849-A | ANTITUMOR AND ANTILEUKEMIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1998-03-17 | — | — | US | disclosed |