Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085861 | 0.78 | KCNN4 (0.36) | SMN1; SMN2KMT2AKIF11TDP1TSHR | |
| SCHEMBL3789477 | 0.74 | CYP2C19 (0.40) | SMN1; SMN2LMNAKMT2ACTSKPOLB | |
| SCHEMBL3997658 | 0.70 | ALDH1A1 (0.34) | SMN1; SMN2TDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL9261168 | 0.68 | MAPT (0.34) | LMNANPC1RAB9AKMT2AKIF11 | |
| SCHEMBL27530901 | 0.68 | LTA4H (0.41) | SMN1; SMN2LMNANPC1RAB9AKMT2A | |
| SCHEMBL27663466 | 0.66 | TSHR (0.45) | SMN1; SMN2LMNAKMT2APPARGPPARA | |
| SCHEMBL28821829 | 0.66 | CTSK (0.38) | NPC1RAB9AKMT2ACTSKMEN1 | |
| Hydrochloric Acid SCHEMBL29208958 | 0.66 | LMNA (0.40) | LMNARAB9AKMT2APOLBTSHR | |
| SCHEMBL10490529 | 0.65 | LTA4H (0.44) | KMT2AKIF11TDP1TSHRL3MBTL1 | |
| SCHEMBL8563142 | 0.65 | EDNRB (0.34) | KMT2AKIF11POLBEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176957-A1 | METHOD FOR TREATING ABNORMAL CELL PROLIFERATION IN THE BRAIN | Aventis Pharma S.A. (FR) | 2002-02-06 | — | — | EP | claimed |
| WO-2000066113-A1 | METHOD FOR TREATING ABNORMAL CELL PROLIFERATION IN THE BRAIN | AVENTIS PHARMA S.A. (FR) | 2000-11-09 | — | — | WO | claimed |