Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21594965 | 0.82 | ADORA3 (0.45) | CHUKLRRK2JAK2JAK1CDK2 | |
| SCHEMBL8826250 | 0.80 | JAK2 (0.46) | CHUKLRRK2JAK2JAK1FFAR2 | |
| SCHEMBL8348019 | 0.78 | NLRP3 (0.40) | CHUKCDK1CDK2CCNB1CCNA2 | |
| SCHEMBL8563173 | 0.78 | CDK1 (0.58) | CHUKCDK1CDK2CCNB1CCNA2 | |
| SCHEMBL133156 | 0.77 | CHUK (0.45) | CHUKJAK1ADORA2A | |
| SCHEMBL30590050 | 0.77 | CHUK (0.45) | CHUKJAK1ADORA2A | |
| SCHEMBL10838740 | 0.77 | NUDT1 (0.41) | CHUKAPPCDK1TLR7PRKACA | |
| SCHEMBL27870443 | 0.76 | GRM4 (0.45) | APPJAK2JAK1CDK1CDK2 | |
| SCHEMBL27870418 | 0.76 | GRM4 (0.42) | APPNOS3NOS1JAK2JAK1 | |
| SCHEMBL8826182 | 0.76 | APP (0.47) | APPTLR7PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817639-A | VIRICIDES | YAMASA CORPORATION (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5811408-A | ANTITUMOR AND ANTICARCINOGENIC AGENT; INTRODUCING SULFONYL GROUP ON HYDROXY GROUP OF TETRAHYDROFURAN RING, HYDROLYSIS, BLOCKING, OXIDATION, WITTING REACTION, DEPROTECTION AND PHOSPHORYLATION | YAMASA CORPORATION (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0770621-A1 | 2'-DEOXY-2'-(SUBSTITUTED OR UNSUBSTITUTED METHYLIDENE)-4'-THIONUCLEOSIDE | YAMASA CORPORATION (JP) | 1997-05-02 | — | — | EP | disclosed |
| EP-0648218-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001443-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |
| US-5153318-A | Viricides for hepatitis and human t-cell leukemia/lymphoma viruses | BURROUGHS WELLCOME CO. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0421739-A1 | 3'-azido purine nucleoside | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-04-10 | — | — | EP | disclosed |