Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558945 | 0.77 | ALDH1A1 (0.47) | HPGDMAPTALDH1A1HSD17B10POLB | |
| SCHEMBL8560680 | 0.75 | KDM4E (0.50) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL31663015 | 0.72 | SMN1; SMN2 (0.58) | USP2HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28756536 | 0.72 | SMN1; SMN2 (1.00) | HPGDSMN1; SMN2MAPTALDH1A1HSD17B10 | |
| SCHEMBL6838324 | 0.72 | SMN1; SMN2 (0.66) | USP2HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL15179293 | 0.71 | SMN1; SMN2 (0.54) | USP2HPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL31663198 | 0.70 | SMN1; SMN2 (0.56) | USP2HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31663234 | 0.70 | HPGD (0.71) | USP2HPGDSMN1; SMN2MAPTALDH1A1 | |
| Acreozast SCHEMBL6454819 | 0.70 | GPR35 (0.59) | USP2HPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8568419 | 0.70 | KMT2A (0.41) | USP2HPGDALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |