SCHEMBL6838324

SCHEMBL6838324

CC(=O)OCC(=O)Nc1ccc(C)cc1O

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.66
HPGD P15428 2/20 0.57
USP2 O75604 1/20 0.57
KDM4E B2RXH2 2/20 0.56
KMT2A Q03164 2/20 0.56
POLB P06746 3/20 0.54
ALDH1A1 P00352 2/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 3/20 0.50
HTT P42858 2/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
PKM P14618 1/20 0.49
CXCR2 P25025 1/20 0.49
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763193 0.84 KMT2A (0.59) SMN1; SMN2HPGDKDM4EKMT2APOLB
SCHEMBL18710355 0.81 SMN1; SMN2 (0.61) SMN1; SMN2HPGDUSP2KMT2APOLB
SCHEMBL6836552 0.79 KMT2A (0.61) SMN1; SMN2KMT2AALDH1A1LMNAGAA
SCHEMBL6838424 0.79 LMNA (0.56) SMN1; SMN2KMT2AALDH1A1LMNAGAA
SCHEMBL9400361 0.78 KMT2A (0.81) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL6572962 0.78 ALDH1A1 (0.73) SMN1; SMN2KDM4EKMT2AALDH1A1LMNA
SCHEMBL7764411 0.78 KMT2A (0.54) SMN1; SMN2KMT2AALDH1A1LMNAGAA
SCHEMBL4520067 0.77 NPC1 (0.69) SMN1; SMN2HPGDKDM4EKMT2APOLB
SCHEMBL28515684 0.76 KMT2A (0.57) SMN1; SMN2KMT2AALDH1A1LMNAGAA
SCHEMBL6836397 0.76 GAA (0.59) KMT2APOLBALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US claimed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US disclosed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US disclosed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed