Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562488 | 0.92 | HSD11B1 (0.39) | HSD11B1NOTUMHDAC4OPRL1PDK2 | |
| SCHEMBL7511121 | 0.91 | HSD11B1 (0.39) | HSD11B1NOTUMHDAC4OPRL1PDK2 | |
| SCHEMBL7507861 | 0.90 | S1PR1 (0.38) | HSD11B1NOTUMHDAC4OPRL1 | |
| SCHEMBL8559067 | 0.89 | NOTUM (0.40) | HSD11B1NOTUMHDAC4OPRL1PDK2 | |
| SCHEMBL8045475 | 0.81 | GLA (0.41) | L3MBTL1 | |
| SCHEMBL7507058 | 0.79 | PDE4B (0.41) | L3MBTL1 | |
| SCHEMBL15043623 | 0.78 | ESR1 (0.44) | HDAC4 | |
| SCHEMBL7513588 | 0.77 | CASP1 (0.41) | HDAC4OPRL1L3MBTL1 | |
| SCHEMBL8725831 | 0.77 | CYSLTR2 (0.43) | — | |
| SCHEMBL10787675 | 0.77 | HDAC4 (0.40) | NOTUMHDAC4OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |