Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563384 | 0.89 | HSD11B1 (0.40) | NOTUMHDAC4HSD11B1OPRL1L3MBTL1 | |
| SCHEMBL8562488 | 0.87 | HSD11B1 (0.39) | NOTUMHDAC4HSD11B1OPRL1PDK2 | |
| SCHEMBL7511121 | 0.85 | HSD11B1 (0.39) | NOTUMHDAC4HSD11B1OPRL1PDK2 | |
| SCHEMBL7507861 | 0.84 | S1PR1 (0.38) | NOTUMHDAC4HSD11B1OPRL1 | |
| SCHEMBL805453 | 0.79 | HDAC4 (0.40) | HDAC4OPRL1HTR2A | |
| SCHEMBL10787675 | 0.77 | HDAC4 (0.40) | NOTUMHDAC4OPRL1 | |
| SCHEMBL805452 | 0.76 | ESR1 (0.43) | HDAC4HSD11B1OPRL1 | |
| SCHEMBL7507973 | 0.76 | VCP (0.37) | NOTUMHDAC4HSD11B1OPRL1 | |
| SCHEMBL7511850 | 0.74 | IDH1 (0.36) | — | |
| SCHEMBL7513588 | 0.71 | CASP1 (0.41) | HDAC4OPRL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |