Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596253 | 0.84 | CYP19A1 (0.40) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30681720 | 0.78 | NPC1 (0.46) | MAPTALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL27143261 | 0.78 | NPC1 (0.46) | MAPTALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL8921703 | 0.78 | MAPT (0.38) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL8566919 | 0.74 | MGMT (0.53) | MAPTKMT2AMEN1HTTMGMT | |
| SCHEMBL8566254 | 0.73 | IKBKB (0.42) | MAPTALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL8566844 | 0.73 | MEN1 (0.40) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8563438 | 0.72 | RAB9A (0.50) | MAPTALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL23352311 | 0.71 | NPC1 (0.53) | MAPTALDH1A1NPC1RAB9ARECQL | |
| SCHEMBL22072961 | 0.71 | MAPT (0.56) | MAPTALDH1A1NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |