Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19172441 | 0.88 | NPC1 (0.50) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8595772 | 0.84 | LMNA (0.50) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL28087330 | 0.83 | ALDH1A1 (0.50) | RAB9ANPC1RECQLKMT2AALDH1A1 | |
| SCHEMBL2241497 | 0.80 | ALDH1A1 (0.56) | RAB9AKMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1340747 | 0.78 | RAB9A (0.83) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8567652 | 0.77 | HTT (0.42) | RAB9ANPC1KMT2AALDH1A1LMNA | |
| SCHEMBL8569165 | 0.75 | CYP11B1 (0.54) | RAB9ANPC1RECQLKMT2AALDH1A1 | |
| SCHEMBL14839601 | 0.74 | ALDH1A1 (0.76) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL10582387 | 0.74 | ALDH1A1 (0.76) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL31327471 | 0.74 | LMNA (0.51) | RAB9ANPC1RECQLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |