Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601231 | 0.79 | L3MBTL1 (0.35) | MAPTALDH1A1POLBLMNAHTT | |
| SCHEMBL8563633 | 0.78 | MAPT (0.37) | MAPTALDH1A1POLBHTTNPC1 | |
| SCHEMBL8564427 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1POLBHPGDLMNA | |
| SCHEMBL8566844 | 0.74 | MEN1 (0.40) | MAPTALDH1A1POLBHPGDLMNA | |
| SCHEMBL8598691 | 0.72 | IMPDH2 (0.32) | MAPTALDH1A1POLBTDP1 | |
| SCHEMBL8565117 | 0.72 | MAPT (0.39) | MAPTALDH1A1LMNAHTTNPC1 | |
| SCHEMBL8567652 | 0.71 | HTT (0.42) | MAPTALDH1A1POLBLMNAHTT | |
| SCHEMBL8564450 | 0.70 | MAPT (0.41) | MAPTALDH1A1POLBHPGDLMNA | |
| SCHEMBL8560215 | 0.70 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL8564571 | 0.69 | MAPT (0.43) | MAPTALDH1A1LMNAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |