Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8564421 | 0.99 | TMEM97 (0.36) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL8560327 | 0.91 | BRD4 (0.33) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| SCHEMBL8559776 | 0.91 | HTR6 (0.35) | TMEM97SIGMAR1HTR6MAPTNOTUM | |
| Hydrochloric Acid SCHEMBL8564477 | 0.90 | HTR6 (0.34) | TMEM97SIGMAR1HTR6MAPT | |
| Hydrochloric Acid SCHEMBL8564921 | 0.84 | INSR (0.34) | TMEM97SIGMAR1ALDH1A1HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL8569203 | 0.82 | HTR6 (0.34) | HTR2CHTR2BHTR6HRH3 | |
| SCHEMBL8563245 | 0.81 | ESR1 (0.38) | TMEM97SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL8558180 | 0.80 | MMP1 (0.32) | HTR2CHTR2BHTR6HRH3 | |
| Iodide SCHEMBL8600500 | 0.80 | ACHE (0.38) | TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL8560509 | 0.79 | TMEM97 (0.42) | TMEM97SIGMAR1SLC6A2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |