Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568619 | 0.90 | ROCK2 (0.56) | ROCK2MAPTMCHR1KMT2AKCNH2 | |
| SCHEMBL8568624 | 0.90 | ROCK2 (0.56) | ROCK2MAPTMCHR1KMT2AKCNH2 | |
| SCHEMBL1514921 | 0.76 | MEN1 (0.50) | ROCK2KMT2APOLBSIGMAR1 | |
| SCHEMBL8285848 | 0.74 | ROCK2 (0.53) | ROCK2MAPTMCHR1KMT2AGRM2 | |
| SCHEMBL14301512 | 0.74 | ROCK2 (0.53) | ROCK2MAPTMCHR1KMT2AKCNH2 | |
| SCHEMBL8788607 | 0.74 | DRD2 (0.50) | ROCK2MCHR1KCNH2DRD2DRD3 | |
| SCHEMBL892458 | 0.74 | ROCK2 (0.53) | ROCK2MAPTMCHR1KMT2APOLB | |
| SCHEMBL892517 | 0.74 | ROCK2 (0.53) | ROCK2MAPTMCHR1KMT2APOLB | |
| Bromide SCHEMBL8897811 | 0.72 | MAPT (0.49) | ROCK2MAPTMCHR1KMT2AGRM2 | |
| Bromide SCHEMBL8563694 | 0.72 | MAPT (0.49) | ROCK2MAPTMCHR1KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |