Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563761 | 1.00 | RAB9A (0.49) | RAB9AMAPK1ANPEPSRCCASP3 | |
| SCHEMBL27554761 | 0.84 | ANPEP (0.52) | RAB9AMAPK1ANPEPSRCCASP3 | |
| SCHEMBL8562675 | 0.82 | HPGD (0.49) | RAB9AANPEPPOLBTP53ALDH1A1 | |
| SCHEMBL8562678 | 0.82 | HPGD (0.49) | RAB9AANPEPPOLBTP53ALDH1A1 | |
| SCHEMBL8568653 | 0.82 | MMP8 (0.51) | ALDH1A1 | |
| SCHEMBL8568656 | 0.82 | MMP8 (0.51) | ALDH1A1 | |
| SCHEMBL8561171 | 0.80 | ALDH1A1 (0.56) | ANPEPPOLBEPHX2KDM4EHSD17B10 | |
| SCHEMBL8561177 | 0.80 | ALDH1A1 (0.56) | ANPEPPOLBEPHX2KDM4EHSD17B10 | |
| SCHEMBL16874806 | 0.78 | CARM1 (0.41) | TP53 | |
| SCHEMBL13797510 | 0.78 | ANPEP (0.60) | RAB9AMAPK1ANPEPSRCCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |