Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565287 | 0.85 | CHRM3 (0.53) | CHRM3MEN1KMT2APOLBCHRM1 | |
| SCHEMBL8570499 | 0.85 | CHRM3 (0.55) | CHRM3MEN1KMT2ACHRM2ACHE | |
| SCHEMBL6167993 | 0.85 | MEN1 (0.59) | CHRM3MEN1KMT2APOLBCHRM2 | |
| SCHEMBL29445321 | 0.84 | OPRL1 (0.52) | CHRM3MEN1KMT2ACHRM2ACHE | |
| SCHEMBL6168606 | 0.84 | OPRL1 (0.52) | CHRM3MEN1KMT2ACHRM2ACHE | |
| SCHEMBL6166562 | 0.83 | CHRM3 (0.55) | CHRM3MEN1KMT2ACHRM2ACHE | |
| SCHEMBL6165994 | 0.82 | CHRM1 (0.48) | CHRM3CHRM1ACHECXCR3ALDH1A1 | |
| SCHEMBL8564971 | 0.82 | TACR1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8565700 | 0.82 | CHRM3 (0.56) | CHRM3KMT2ACHRM2SIGMAR1CXCR3 | |
| SCHEMBL8568996 | 0.81 | KDM1A (0.49) | CHRM3MEN1KMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |