Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445321 | 0.88 | OPRL1 (0.52) | CHRM3OPRM1DRD4DRD2MEN1 | |
| SCHEMBL6168606 | 0.88 | OPRL1 (0.52) | CHRM3OPRM1DRD4DRD2MEN1 | |
| SCHEMBL8569508 | 0.86 | MEN1 (0.53) | CHRM3OPRM1DRD4ALDH1A1DRD2 | |
| SCHEMBL6165994 | 0.85 | CHRM1 (0.48) | CHRM3ALDH1A1CHRM1 | |
| SCHEMBL8563876 | 0.85 | CHRM3 (0.54) | CHRM3POLBALDH1A1CXCR4CHRM1 | |
| SCHEMBL6168165 | 0.83 | CHRM3 (0.49) | CHRM3OPRM1DRD4ALDH1A1DRD2 | |
| SCHEMBL8564971 | 0.83 | TACR1 (0.43) | OPRM1DRD4ALDH1A1DRD2MEN1 | |
| SCHEMBL8565096 | 0.83 | CCR5 (0.48) | CHRM3SIGMAR1 | |
| SCHEMBL8568112 | 0.82 | MAOA (0.41) | CHRM3DRD4CHRM1DRD2SIGMAR1 | |
| SCHEMBL8564439 | 0.82 | CHRM2 (0.55) | CHRM3OPRM1DRD4ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |