Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 5/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567952 | 0.85 | SLC18A3 (0.49) | KDM1ASLC18A3PDE6DTACR1 | |
| SCHEMBL8564971 | 0.85 | TACR1 (0.43) | PDE6DMEN1KMT2ATACR1DRD2 | |
| SCHEMBL8571012 | 0.84 | CHRM2 (0.49) | CHRM2CHRM3MEN1KMT2ADRD2 | |
| SCHEMBL8564042 | 0.84 | CHRM2 (0.43) | KDM1ACALCRLCHRM2CHRM3MEN1 | |
| SCHEMBL6168606 | 0.83 | OPRL1 (0.52) | CHRM2CHRM3MEN1KMT2ADRD2 | |
| SCHEMBL29445321 | 0.83 | OPRL1 (0.52) | CHRM2CHRM3MEN1KMT2ADRD2 | |
| SCHEMBL6168284 | 0.82 | TACR1 (0.41) | CALCRLSLC18A3CHRM3PDE6DMEN1 | |
| SCHEMBL8570499 | 0.82 | CHRM3 (0.55) | CHRM2CHRM3MEN1KMT2ADRD2 | |
| SCHEMBL6168102 | 0.82 | CHRM3 (0.42) | CALCRLCHRM3PARP1TACR1DRD2 | |
| SCHEMBL8563876 | 0.81 | CHRM3 (0.54) | CHRM2CHRM3MEN1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |