Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17041577 | 0.86 | MAOB (0.52) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL25365036 | 0.82 | CTSV (0.52) | MAPTTDP1L3MBTL1LMNAHPGD | |
| SCHEMBL24379393 | 0.80 | CTSV (0.50) | MAPTLMNAHPGDCTSVCTSL | |
| SCHEMBL31543962 | 0.80 | KCNA2 (0.44) | MAOBBRD4LMNAHPGDMAOA | |
| SCHEMBL25368457 | 0.80 | GLRA1 (0.46) | MAOBSMN1; SMN2BRD4LMNAHPGD | |
| SCHEMBL14882664 | 0.79 | CTSV (0.52) | BRD4LMNAHPGDCTSVCTSL | |
| SCHEMBL25365865 | 0.79 | CTSV (0.49) | MAPTLMNAHPGDCTSVCTSL | |
| SCHEMBL17191960 | 0.79 | BRD4 (0.56) | MAOBSMN1; SMN2BRD4LMNAHPGD | |
| SCHEMBL25367668 | 0.79 | ALDH1A1 (0.51) | TDP1L3MBTL1LMNAHPGDCTSV | |
| SCHEMBL24379392 | 0.79 | LMNA (0.54) | MAPTTDP1BRD4LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |