Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561264 | 0.82 | S1PR4 (0.39) | ALDH1A1MAPTS1PR4LMNASMN1; SMN2 | |
| SCHEMBL8602297 | 0.79 | L3MBTL1 (0.40) | ALDH1A1MAPTS1PR4POLBHTT | |
| SCHEMBL8569178 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAPOLBHTT | |
| SCHEMBL2794197 | 0.76 | LMNA (0.36) | ALDH1A1LMNA | |
| SCHEMBL8563926 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL8563923 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL8596319 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MAPTPOLBHTT | |
| SCHEMBL8564571 | 0.73 | MAPT (0.43) | ALDH1A1MAPTLMNAHTTRAB9A | |
| SCHEMBL8568292 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTS1PR4LMNAPOLB | |
| SCHEMBL28046347 | 0.73 | HTT (0.42) | ALDH1A1MAPTLMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |