SCHEMBL8569178

SCHEMBL8569178

Nc1cnc([N+](=O)[O-])c(CCl)c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TSHR P16473 3/20 0.37
ALOX15 P16050 2/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP3A4 P08684 1/20 0.31
IDO1 P14902 1/20 0.30
HIF1A Q16665 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8596319 0.80 ALDH1A1 (0.32) ALDH1A1ALOX15HPGDPOLBHTT
SCHEMBL8564259 0.76 ALDH1A1 (0.37) ALDH1A1POLBHTTMAPTKDM4E
SCHEMBL8602297 0.76 L3MBTL1 (0.40) ALDH1A1HPGDPOLBHTTMAPT
SCHEMBL8568534 0.76 CYP19A1 (0.40) POLBHTTMAPTLMNA
SCHEMBL8568828 0.76 TDP1 (0.48) ALDH1A1TSHRALOX15HPGDPOLB
SCHEMBL8562235 0.76 TDP1 (0.48) ALDH1A1TSHRALOX15HPGDPOLB
SCHEMBL8559630 0.75 IDO1 (0.33) ALDH1A1TSHRALOX15HPGDHTT
SCHEMBL8559625 0.75 IDO1 (0.33) ALDH1A1TSHRALOX15HPGDHTT
SCHEMBL8566803 0.74 ALOX15 (0.44) ALDH1A1TSHRALOX15HPGDHTT
SCHEMBL28076647 0.73 MAPT (0.45) ALDH1A1TSHRALOX15HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed