Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562989 | 0.83 | ALDH1A1 (1.00) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL11627068 | 0.83 | ALDH1A1 (0.74) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL17595755 | 0.82 | NOTUM (1.00) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL20029259 | 0.80 | SIRT2 (0.91) | SIRT2ALDH1A1NOTUML3MBTL1RAB9A | |
| Dimethylamine SCHEMBL7961651 | 0.80 | ALDH1A1 (0.61) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL7961634 | 0.80 | HTR1A (0.65) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL14288613 | 0.79 | RAB9A (0.70) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL14736563 | 0.79 | RAB9A (0.70) | ALDH1A1NOTUML3MBTL1RAB9ANPC1 | |
| SCHEMBL15504863 | 0.79 | RAB9A (0.70) | SIRT2ALDH1A1NOTUML3MBTL1RAB9A | |
| SCHEMBL15633901 | 0.79 | L3MBTL1 (0.73) | SIRT2ALDH1A1NOTUML3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059445-C | Novel derivatives of erythromycin, their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-12-13 | — | — | CN | disclosed |
| US-5760233-A | CHEMICAL INTERMEDIATES FOR MAKING ERYTHROMYCINS ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5656607-A | Erythromycin derivatives | ROUSSEL UCLAF (FR) | 1997-08-12 | — | — | US | disclosed |
| CN-1126997-A | Novel erythromycin derivatives, method for preparing same and use thereof as drugs | ROUSSEL UCLAF (FR) | 1996-07-17 | — | — | CN | disclosed |