Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569140 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL8566577 | 0.78 | HTR1A (0.42) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL8569210 | 0.75 | HTR1A (0.62) | LMNAALDH1A1HTTHTR1ADRD2 | |
| SCHEMBL8564814 | 0.75 | MAPT (0.45) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL444075 | 0.75 | KDM4E (0.40) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL12000335 | 0.74 | MAPT (0.45) | SMN1; SMN2HPGDMAPTLMNANPC1 | |
| SCHEMBL8723876 | 0.72 | HPGD (0.53) | SMN1; SMN2HPGDMAPTALDH1A1HTT | |
| SCHEMBL11298886 | 0.72 | HPGD (0.41) | SMN1; SMN2HPGDMAPTLMNAALDH1A1 | |
| SCHEMBL8564591 | 0.71 | HTR1A (0.64) | HPGDMAPTLMNAALDH1A1HTR1A | |
| SCHEMBL8566180 | 0.71 | HTR1A (0.41) | HPGDMAPTLMNAALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |