Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 3/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740129 | 0.81 | KDM4E (0.37) | HPGDALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL7839044 | 0.79 | PLA2G7 (0.40) | HPGDCYP1A2CYP2A6PLA2G7HSD11B1 | |
| SCHEMBL6682355 | 0.78 | CYP2A6 (0.40) | STK10SLKHPGDGSK3BHSP90AA1 | |
| SCHEMBL9138237 | 0.75 | HSD11B1 (0.41) | STK10SLKHPGDHSP90AA1CYP2A6 | |
| SCHEMBL5528999 | 0.75 | NPC1 (0.39) | HPGDCYP2A6PLA2G7HSD11B1ALDH1A1 | |
| SCHEMBL5670544 | 0.75 | MEN1 (0.40) | CYP1A2CYP2A6ALDH1A1KMT2AMEN1 | |
| SCHEMBL6191708 | 0.74 | PTGS2 (0.38) | HPGDALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7465625 | 0.74 | CYP2A6 (0.50) | HPGDCYP1A2CYP2A6HSD11B1ALDH1A1 | |
| SCHEMBL1009593 | 0.71 | — | — | |
| SCHEMBL2113995 | 0.71 | CYP2A6 (0.44) | HPGDCYP2A6HSD11B1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |