Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524890 | 0.80 | MASP2 (0.44) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL17329324 | 0.77 | KMT2A (0.42) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL14365376 | 0.70 | MEN1 (0.44) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL2735452 | 0.70 | TLR8 (0.46) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL14472200 | 0.68 | KIF11 (0.47) | PARP1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL8864413 | 0.68 | TP53 (0.35) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL727229 | 0.68 | ALDH1A1 (0.48) | PARP1MASP2MEN1ALDH1A1NUDT1 | |
| SCHEMBL473376 | 0.68 | ALDH1A1 (0.39) | PARP1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3287768 | 0.67 | ALDH1A1 (0.52) | PARP1MASP2MEN1ALDH1A1NUDT1 | |
| Hydrochloric Acid SCHEMBL473352 | 0.66 | ALDH1A1 (0.38) | PARP1MEN1ALDH1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |