Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524890 | 0.76 | MASP2 (0.44) | MEN1KMT2AALDH1A1HPGDMASP2 | |
| SCHEMBL17329324 | 0.73 | KMT2A (0.42) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7745378 | 0.71 | DPP4 (0.46) | POLBKMT2ADPP4ALDH1A1KCNA5 | |
| SCHEMBL18108809 | 0.68 | ALDH1A1 (0.41) | POLBKMT2AALDH1A1KDM4EKCNA5 | |
| SCHEMBL8564912 | 0.68 | PARP1 (0.39) | MEN1KMT2AALDH1A1MASP2NUDT1 | |
| SCHEMBL11361681 | 0.68 | SLC6A2 (0.39) | POLBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12248160 | 0.67 | KCNA5 (0.46) | DPP4ALDH1A1KDM4EKCNA5LTA4H | |
| SCHEMBL5323911 | 0.66 | P4HB (0.45) | DPP4ALDH1A1HPGDGAAKCNA5 | |
| SCHEMBL1203109 | 0.66 | CYP2D6 (0.46) | PIK3CDALDH1A1GAAKCNA5LTA4H | |
| SCHEMBL29336310 | 0.66 | ATR (0.39) | ALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |