Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570205 | 0.91 | MEN1 (0.41) | TACR1TP53MAPK1HSD17B10MEN1 | |
| SCHEMBL8564525 | 0.86 | CYP1A2 (0.52) | TACR1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8567952 | 0.86 | SLC18A3 (0.49) | TACR1KDM1AOPRL1 | |
| SCHEMBL6168606 | 0.86 | OPRL1 (0.52) | MEN1KMT2AOPRL1CHRM2CHRM3 | |
| SCHEMBL8564971 | 0.86 | TACR1 (0.43) | TACR1MEN1KMT2AALDH1A1OPRL1 | |
| SCHEMBL29445321 | 0.86 | OPRL1 (0.52) | MEN1KMT2AOPRL1CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL8597954 | 0.85 | CYP1A2 (0.51) | TACR1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6168102 | 0.85 | CHRM3 (0.42) | TACR1CALCRLOPRL1CHRM3CCR5 | |
| SCHEMBL8571012 | 0.83 | CHRM2 (0.49) | TP53MEN1KMT2AOPRL1CHRM2 | |
| SCHEMBL8571710 | 0.83 | PRCP (0.42) | TACR1HSD17B10GAAALDH1A1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |