Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | PDE6D | O43924 | 5/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571012 | 0.87 | CHRM2 (0.49) | OPRL1SIGMAR1ACHE | |
| SCHEMBL8565908 | 0.86 | TACR1 (0.41) | KDM1ATACR1OPRL1 | |
| SCHEMBL6168606 | 0.86 | OPRL1 (0.52) | OPRL1OPRM1ACHE | |
| SCHEMBL29445321 | 0.86 | OPRL1 (0.52) | OPRL1OPRM1ACHE | |
| SCHEMBL8564971 | 0.86 | TACR1 (0.43) | PDE6DTACR1OPRL1OPRM1 | |
| SCHEMBL8568996 | 0.85 | KDM1A (0.49) | SLC18A3KDM1APDE6DTACR1 | |
| SCHEMBL6168102 | 0.85 | CHRM3 (0.42) | TACR1OPRL1OPRM1ACHE | |
| SCHEMBL8570205 | 0.84 | MEN1 (0.41) | KDM1APDE6DTACR1 | |
| SCHEMBL8564042 | 0.84 | CHRM2 (0.43) | KDM1ATACR1 | |
| SCHEMBL8571710 | 0.83 | PRCP (0.42) | PDE6DTACR1OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |