Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700032 | 0.82 | PAX8 (0.42) | ALDH1A1KMT2AMEN1RAB9AMET | |
| SCHEMBL31028752 | 0.82 | CA1 (0.50) | ALDH1A1KMT2AMEN1RAB9AMET | |
| SCHEMBL8562081 | 0.82 | CA1 (0.50) | ALDH1A1KMT2AMEN1RAB9AMET | |
| SCHEMBL27444563 | 0.77 | KMT2A (0.48) | ALDH1A1KMT2AMEN1PKMOPRK1 | |
| SCHEMBL8561302 | 0.76 | NT5E (0.41) | ALDH1A1CYP1A2ALOX15HIF1AHSD17B10 | |
| SCHEMBL27463580 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CYP1A2HSD17B10KMT2AMEN1 | |
| SCHEMBL8597763 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1RAB9AMET | |
| SCHEMBL8563296 | 0.74 | ALDH1A1 (0.51) | ALDH1A1CYP1A2ALOX15HIF1AHSD17B10 | |
| SCHEMBL245234 | 0.73 | MAPT (0.50) | ALDH1A1KMT2AMEN1RAB9APKM | |
| SCHEMBL30954607 | 0.73 | MAPT (0.50) | ALDH1A1KMT2AMEN1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616933-B | Novel anti-CD 38 antibodies for the treatment of cancer | SANOFI AVENTIS | 2015-06-10 | — | — | CN | disclosed |
| CN-101622276-B | Antagonistic antibodies against EPHA2 for the treatment of cancer | SANOFI AVENTIS | 2015-04-22 | — | — | CN | disclosed |
| CN-101331400-B | Methods for generating multimeric capture agents that bind ligands | SHARP KK | 2012-09-26 | — | — | CN | disclosed |
| CN-101317093-B | Novel capture reagents for binding ligands | SHARP KK | 2012-09-19 | — | — | CN | disclosed |
| CN-102076717-A | Crosslinking agents and their use | IMMUNOGEN INC | 2011-05-25 | — | — | CN | disclosed |
| CN-101622276-A | Antagonistic antibodies against EPHA2 for the treatment of cancer | SANOFI AVENTIS | 2010-01-06 | — | — | CN | disclosed |
| CN-101616933-A | Novel anti-CD 38 antibodies for the treatment of cancer | SANOFI AVENTIS | 2009-12-30 | — | — | CN | disclosed |
| CN-101331400-A | A method of producing a multimeric capture agent for binding a ligand | SHARP KK (JP) | 2008-12-24 | — | — | CN | disclosed |
| CN-101317093-A | Novel capture reagents for binding ligands | SHARP KK (JP) | 2008-12-03 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |