Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562081 | 1.00 | CA1 (0.50) | CA1CA2CA9MAPK1MAPT | |
| SCHEMBL27463580 | 0.87 | ALDH1A1 (0.45) | CA1CA2CA9MAPK1MAPT | |
| SCHEMBL8564974 | 0.82 | ALDH1A1 (0.44) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL5700032 | 0.82 | PAX8 (0.42) | NPY1RMEN1KMT2ARAB9AMET | |
| SCHEMBL8565961 | 0.77 | CA2 (0.39) | CA1CA2CA9MAPK1MAPT | |
| SCHEMBL8597763 | 0.74 | ALDH1A1 (0.57) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL8563296 | 0.74 | ALDH1A1 (0.51) | MAPK1MAPTCYP2C9LMNAMEN1 | |
| SCHEMBL27444563 | 0.73 | KMT2A (0.48) | MAPTFTOMEN1KMT2AHTT | |
| SCHEMBL601835 | 0.73 | HTT (0.50) | MAPTCYP2C9LMNAMEN1KMT2A | |
| SCHEMBL30954607 | 0.73 | MAPT (0.50) | MAPTLMNAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | disclosed |