Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565961 | 0.85 | CA2 (0.39) | NT5EALDH1A1CYP2C19CYP1A2CA12 | |
| SCHEMBL8560999 | 0.77 | HTT (0.41) | NT5EKDM4ENSD2GAAPLCG1 | |
| SCHEMBL8602563 | 0.76 | ALDH1A1 (0.42) | KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8564974 | 0.76 | ALDH1A1 (0.44) | KDM4EGAACASP6ALDH1A1CYP1A2 | |
| SCHEMBL3709618 | 0.75 | GAA (0.39) | KDM4EGAACASP6L3MBTL1ALDH1A1 | |
| SCHEMBL8562148 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1TSHRCYP2C19CYP1A2 | |
| SCHEMBL8141010 | 0.74 | HTT (0.37) | ALDH1A1TSHRALOX15ROCK1POLB | |
| SCHEMBL8596152 | 0.74 | RECQL (0.43) | KDM4EL3MBTL1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL8628187 | 0.74 | CA12 (0.35) | CA12CA1CA2CA9CA7 | |
| SCHEMBL8596657 | 0.74 | TXNRD1 (0.43) | KDM4EGAAL3MBTL1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |