Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569529 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL4612728 | 0.87 | PTGDR2 (0.57) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL656717 | 0.87 | MEN1 (0.56) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL15330191 | 0.80 | KDM4E (0.67) | ALDH1A1KMT2AMEN1MAPTSNCA | |
| SCHEMBL15933189 | 0.80 | KDM4E (0.51) | ALDH1A1KMT2AMEN1MAPTSNCA | |
| SCHEMBL6536100 | 0.78 | LMNA (0.54) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL8562385 | 0.78 | USP2 (0.58) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL28950410 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL11212890 | 0.78 | KMT2A (0.57) | ALDH1A1KMT2AMEN1MAPTSNCA | |
| SCHEMBL8569607 | 0.78 | RAB9A (0.56) | ALDH1A1KMT2AMEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |