Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567023 | 0.83 | NCF1 (0.56) | NQO1NCF1POLBCYP1A2MAPT | |
| SCHEMBL8559109 | 0.79 | HTR3A (0.37) | RXFP1CYP2A6MAPTHDAC1HDAC2 | |
| SCHEMBL5188214 | 0.77 | POLB (0.59) | NQO1NCF1PPARGNCOA2NCOA1 | |
| SCHEMBL15663471 | 0.75 | KDM4E (0.49) | POLBKDM4ECYP1A2CYP2A6MAPT | |
| SCHEMBL5547120 | 0.75 | NPC1 (0.54) | NQO1NCF1POLBKDM4ECYP1A2 | |
| SCHEMBL8565804 | 0.73 | HPGD (0.43) | NCF1NPSR1RXFP1L3MBTL1KDM4E | |
| SCHEMBL30081476 | 0.71 | NCF1 (0.65) | NQO1NCF1PPARGNCOA2NCOA1 | |
| SCHEMBL806266 | 0.71 | NCF1 (0.65) | NQO1NCF1PPARGNCOA2NCOA1 | |
| SCHEMBL920051 | 0.70 | PTGIR (0.52) | POLBCYP1A2MEN1KMT2A | |
| SCHEMBL24241738 | 0.70 | TP53 (0.47) | NCF1NPSR1RXFP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |