Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565366 | 0.84 | ACHE (0.39) | ACHEEPHX2NPY1RNPY4RNPY5R | |
| SCHEMBL8565370 | 0.82 | EPHX2 (0.36) | ACHEEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8653248 | 0.81 | HDAC3 (0.41) | ACHEEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8653244 | 0.81 | HDAC3 (0.41) | ACHEEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8657504 | 0.81 | HDAC3 (0.41) | ACHEEPHX2HDAC3HDAC4HDAC1 | |
| Anisperimus SCHEMBL8778912 | 0.80 | FAAH (0.39) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| Anisperimus SCHEMBL8778920 | 0.80 | FAAH (0.39) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| Anisperimus SCHEMBL8778901 | 0.80 | FAAH (0.39) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL8601060 | 0.78 | ACHE (0.33) | ACHENPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL526029 | 0.78 | MEN1 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743300-B1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER IND & SANTE (FR) | 1999-08-04 | — | — | EP | disclosed |
| EP-0743300-A1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1996-11-20 | — | — | EP | disclosed |