Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565358 | 0.84 | ACHE (0.36) | ACHEEPHX2NPY1RNPY2RNPY4R | |
| SCHEMBL13399998 | 0.72 | ALOX15 (0.44) | EPHX2CASP2 | |
| SCHEMBL20542788 | 0.71 | ACHE (0.70) | ACHEEPHX2 | |
| Hydrochloric Acid SCHEMBL20542698 | 0.70 | ACHE (0.68) | ACHEEPHX2 | |
| SCHEMBL17754031 | 0.67 | ACHE (0.45) | ACHEEPHX2 | |
| SCHEMBL8412131 | 0.67 | ACHE (0.40) | ACHEEPHX2 | |
| SCHEMBL24087524 | 0.67 | CASP2 (0.65) | EPHX2CASP2L3MBTL1 | |
| SCHEMBL20543068 | 0.67 | CASP2 (0.65) | EPHX2CASP2L3MBTL1 | |
| SCHEMBL21842282 | 0.67 | CASP2 (0.65) | EPHX2CASP2L3MBTL1 | |
| SCHEMBL20542925 | 0.67 | CASP2 (0.65) | EPHX2CASP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743300-B1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER IND & SANTE (FR) | 1999-08-04 | — | — | EP | disclosed |
| EP-0743300-A1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1996-11-20 | — | — | EP | disclosed |