Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 12/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413512 | 0.86 | PAOX (0.38) | EPHX2ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL8412008 | 0.86 | EPHX2 (0.37) | EPHX2ACHE | |
| SCHEMBL8565358 | 0.82 | ACHE (0.36) | EPHX2ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL8653255 | 0.81 | HDAC3 (0.38) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8778905 | 0.80 | FAAH (0.36) | EPHX2ACHE | |
| SCHEMBL8778931 | 0.80 | FAAH (0.36) | EPHX2ACHE | |
| SCHEMBL8778919 | 0.80 | FAAH (0.36) | EPHX2ACHE | |
| SCHEMBL8779144 | 0.78 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL526030 | 0.78 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8778900 | 0.78 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743300-B1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER IND & SANTE (FR) | 1999-08-04 | — | — | EP | disclosed |
| EP-0743300-A1 | 15-Deoxyspergualine-related compounds, process for their preparation and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1996-11-20 | — | — | EP | disclosed |