Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688408 | 0.89 | ZDHHC7 (0.46) | ALDH1A1LMNAKMT2AMAPTHTT | |
| SCHEMBL7971360 | 0.83 | ATM (0.41) | MAPTHSD17B10L3MBTL1ATMZDHHC7 | |
| SCHEMBL27527798 | 0.82 | ZDHHC7 (0.47) | ALDH1A1LMNAL3MBTL1ATMZDHHC7 | |
| SCHEMBL7970865 | 0.82 | ELANE (0.41) | ALDH1A1HSD17B10L3MBTL1ATMZDHHC7 | |
| SCHEMBL27342290 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2AMAPTHTT | |
| SCHEMBL7773448 | 0.79 | ZDHHC7 (0.57) | ALDH1A1LMNAZDHHC7TSHRPRSS1 | |
| SCHEMBL9446493 | 0.78 | KMT2A (0.69) | ALDH1A1LMNAKMT2AMAPTHTT | |
| SCHEMBL9468365 | 0.78 | KMT2A (0.69) | ALDH1A1LMNAKMT2AMAPTHTT | |
| SCHEMBL9154081 | 0.78 | ZDHHC7 (0.61) | ALDH1A1LMNAKMT2AMAPTHTT | |
| SCHEMBL20563362 | 0.77 | KMT2A (0.67) | ALDH1A1LMNAKMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717742-B1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5780633-A | Process for the preparation of indolizine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0717742-A1 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007279-A2 | PROCESS FOR THE PREPARATION OF INDOLIZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |