Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970865 | 0.95 | ELANE (0.41) | ATML3MBTL1TDP1ELANEPRSS1 | |
| SCHEMBL7062133 | 0.90 | ATM (0.44) | ATML3MBTL1TDP1ELANEALOX15 | |
| SCHEMBL27527798 | 0.85 | ZDHHC7 (0.47) | ATML3MBTL1TDP1PRSS1PRSS2 | |
| SCHEMBL8565502 | 0.83 | ALDH1A1 (0.46) | ATML3MBTL1TDP1PRSS1PRSS2 | |
| SCHEMBL7773448 | 0.83 | ZDHHC7 (0.57) | TDP1PRSS1PRSS2PRSS3ZDHHC7 | |
| SCHEMBL9849997 | 0.82 | ATM (0.46) | ATML3MBTL1TDP1ELANEALOX15 | |
| SCHEMBL9436169 | 0.79 | ZDHHC2 (0.61) | PRSS1PRSS2PRSS3ZDHHC7ALOX5 | |
| SCHEMBL7973322 | 0.79 | ALDH1A1 (0.47) | L3MBTL1TDP1HPGDMAPT | |
| SCHEMBL27506827 | 0.78 | L3MBTL1 (0.50) | ATML3MBTL1ELANECYP1A2KDM4E | |
| SCHEMBL262972 | 0.77 | ATM (0.49) | ATML3MBTL1TDP1ELANEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |