Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565506 | 0.89 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL363 | 0.88 | AGTR1 (0.73) | AGTR2AGTR1 | |
| SCHEMBL8562299 | 0.84 | AGTR2 (0.55) | AGTR2AGTR1 | |
| SCHEMBL12112109 | 0.83 | AGTR2 (0.60) | AGTR2AGTR1 | |
| SCHEMBL8565334 | 0.82 | AGTR1 (0.73) | AGTR2AGTR1 | |
| SCHEMBL9650983 | 0.82 | AGTR2 (0.86) | AGTR2EDNRA | |
| SCHEMBL8561980 | 0.81 | AGTR2 (0.51) | AGTR2AGTR1EDNRA | |
| SCHEMBL8569736 | 0.80 | GP6 (0.69) | AGTR2AGTR1 | |
| SCHEMBL809 | 0.80 | AGT (0.57) | AGTR2AGTR1EDNRA | |
| SCHEMBL21083712 | 0.79 | AGTR2 (0.60) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | disclosed |