Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559625 | 1.00 | IDO1 (0.33) | IDO1ALDH1A1HPGDALOX15MAPT | |
| SCHEMBL8562885 | 0.80 | NFE2L2 (0.45) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL8563926 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL8563923 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL8569178 | 0.75 | ALDH1A1 (0.37) | IDO1ALDH1A1HPGDALOX15MAPT | |
| SCHEMBL8568828 | 0.74 | TDP1 (0.48) | ALDH1A1HPGDALOX15MAPTTDP1 | |
| SCHEMBL8562235 | 0.74 | TDP1 (0.48) | ALDH1A1HPGDALOX15MAPTLMNA | |
| SCHEMBL8566803 | 0.73 | ALOX15 (0.44) | IDO1ALDH1A1HPGDALOX15MAPT | |
| SCHEMBL8565614 | 0.72 | MAPT (0.33) | ALDH1A1HPGDALOX15MAPTKDM4E | |
| SCHEMBL8565616 | 0.72 | MAPT (0.33) | ALDH1A1HPGDALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |