Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | MIF | P14174 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366686 | 0.86 | MIF (0.77) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL8566379 | 0.82 | AKR1B10 (0.67) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL1368289 | 0.80 | MEN1 (0.76) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL8566382 | 0.79 | MIF (0.54) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL37883 | 0.79 | MAOA (0.76) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL2471214 | 0.78 | ALDH1A1 (1.00) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL893210 | 0.77 | MEN1 (0.74) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL11070463 | 0.77 | MEN1 (0.71) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL592707 | 0.77 | MEN1 (1.00) | MEN1KMT2AMIFALDH1A1HPGD | |
| SCHEMBL28575753 | 0.77 | MEN1 (0.66) | MEN1KMT2AMIFALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773236-A | FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS | MOLECULE PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |