Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8567040 | 0.99 | LMNA (0.54) | POLBRAD52LMNASLC2A1EHMT2 | |
| SCHEMBL8559967 | 0.86 | PDGFRA (0.48) | POLBRAD52LMNASLC2A1EHMT2 | |
| Hydrochloric Acid SCHEMBL8566059 | 0.85 | HTT (0.50) | POLBRAD52LMNASLC2A1EHMT2 | |
| Water SCHEMBL8328226 | 0.85 | PDGFRA (0.47) | POLBRAD52LMNASLC2A1EHMT2 | |
| SCHEMBL8561356 | 0.78 | PDE4B (0.44) | POLBRAD52LMNASLC2A1MEN1 | |
| SCHEMBL8566080 | 0.76 | PDE4B (0.43) | POLBRAD52SLC2A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8561034 | 0.76 | PDE4B (0.43) | POLBRAD52LMNASLC2A1MEN1 | |
| SCHEMBL8563461 | 0.75 | PDE4B (0.41) | POLBRAD52LMNASLC2A1MEN1 | |
| Hydrochloric Acid SCHEMBL8564884 | 0.75 | MAP2K1 (0.41) | POLBRAD52SLC2A1MEN1KMT2A | |
| SCHEMBL8560347 | 0.74 | ERBB2 (0.52) | POLBRAD52SLC2A1EHMT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| US-5464781-A | TREATING RHEUMATIC DISEASES | THE BOOTS COMPANY PLC (GB) | 1995-11-07 | — | — | US | disclosed |
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |