Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8597954 | 0.99 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL8565908 | 0.86 | TACR1 (0.41) | CYP1A2CYP2C9CYP2C19GAAMEN1 | |
| SCHEMBL8570205 | 0.84 | MEN1 (0.41) | GAAMEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL8564971 | 0.84 | TACR1 (0.43) | MEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL8567952 | 0.80 | SLC18A3 (0.49) | TACR1 | |
| SCHEMBL6168606 | 0.80 | OPRL1 (0.52) | CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL29445321 | 0.80 | OPRL1 (0.52) | CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL8568996 | 0.79 | KDM1A (0.49) | SMN1; SMN2MEN1KMT2ACHRM1LMNA | |
| SCHEMBL6168284 | 0.79 | TACR1 (0.41) | SMN1; SMN2MEN1KMT2AATMTACR1 | |
| SCHEMBL6168102 | 0.79 | CHRM3 (0.42) | TACR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |