Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564430 | 0.80 | KMT2A (0.40) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8567371 | 0.78 | BACE1 (0.55) | C1RIGF1RKMT2AMEN1POLB | |
| SCHEMBL8561607 | 0.76 | MAPT (0.47) | KMT2AMEN1POLBSMN1; SMN2MAPT | |
| SCHEMBL8560946 | 0.74 | MEN1 (0.43) | C1RIGF1RKMT2AMEN1POLB | |
| SCHEMBL8564150 | 0.74 | NCF1 (0.47) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3298254 | 0.73 | KMT2A (0.54) | C1RKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8597322 | 0.73 | NCF1 (0.48) | ALDH1A1SMN1; SMN2GAAMAPTRAB9A | |
| SCHEMBL3956436 | 0.72 | NCF1 (0.51) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8566513 | 0.72 | CASP6 (0.44) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8569955 | 0.72 | KMT2A (0.42) | C1RKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |