Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | MGMT | P16455 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564150 | 0.81 | NCF1 (0.47) | MAPTHTTSMN1; SMN2NPC1LMNA | |
| Quinoline SCHEMBL27547243 | 0.81 | MAPT (0.39) | MAPTHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL8597322 | 0.80 | NCF1 (0.48) | MAPTHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL8566984 | 0.77 | CA1 (0.39) | MAPTHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL8562778 | 0.77 | RIPK1 (0.47) | MAPTSMN1; SMN2NPC1RAB9ANPSR1 | |
| SCHEMBL8567516 | 0.76 | AGTR1 (0.48) | MAPTLMNARAB9AHPGDKMT2A | |
| SCHEMBL4272791 | 0.76 | SMN1; SMN2 (0.53) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5732599 | 0.76 | MAPT (0.53) | MAPTHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL8566013 | 0.76 | C1R (0.41) | MAPTHTTSMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL8564430 | 0.76 | KMT2A (0.40) | MAPTHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |