Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597322 | 0.86 | NCF1 (0.48) | NCF1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8561607 | 0.81 | MAPT (0.47) | NPC1RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL8563057 | 0.81 | POLB (0.46) | NCF1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8564988 | 0.76 | LTB4R (0.45) | NPC1RAB9ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL30438659 | 0.76 | ALOX15 (0.69) | NCF1KDM1ATSHRALDH1A1HPGD | |
| SCHEMBL20515870 | 0.76 | ALOX15 (0.69) | NCF1KDM1ATSHRALDH1A1HPGD | |
| SCHEMBL13372735 | 0.74 | CTSB (0.43) | NPC1RAB9ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL8566013 | 0.74 | C1R (0.41) | RAB9APOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8564430 | 0.74 | KMT2A (0.40) | NPC1RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL30894772 | 0.73 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |