Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143471 | 0.83 | PPARD (0.46) | PTGDR2 | |
| SCHEMBL29960528 | 0.83 | PPARD (0.46) | PTGDR2 | |
| SCHEMBL8144705 | 0.81 | KDM4C (0.37) | PTGDR2KDM4CGAA | |
| SCHEMBL10407804 | 0.81 | SSTR4 (0.38) | PTGDR2SSTR4BDKRB1KCNH2 | |
| SCHEMBL29960371 | 0.81 | POLB (0.45) | PTGDR2SSTR4KCNH2GAA | |
| SCHEMBL8820478 | 0.81 | SSTR4 (0.42) | PTGDR2SSTR4BDKRB1USP2 | |
| SCHEMBL3596582 | 0.81 | POLB (0.45) | PTGDR2SSTR4KCNH2GAA | |
| SCHEMBL27782958 | 0.80 | PSMB5 (0.39) | PTGDR2SSTR4BDKRB1KCNH2KDM4C | |
| SCHEMBL8563821 | 0.79 | HTR1A (0.35) | LTA4HPTGDR2KDM4CDRD2HTR2A | |
| SCHEMBL28452015 | 0.78 | P2RX7 (0.41) | LTA4HSSTR4MEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756496-A | Amide derivatives having 5HT1D-antagonist activity | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-05-26 | — | — | US | disclosed |
| EP-0763034-A1 | AMIDE DERIVATIVES HAVING 5HT1D-ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032967-A1 | AMIDE DERIVATIVES HAVING 5HT1D-ANTAGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-12-07 | — | — | WO | disclosed |